HNRNPKP5

Across TCGA patient cohorts, HNRNPKP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,993 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HNRNPKP5-associated GO terms across cancer lineages are Golgi lumen acidification, Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Positive regulation of amide metabolic process. Each is linked with HNRNPKP5 in more than 20 cancer types. Because this analysis shows association rather than direction, both HNRNPKP5-to-partner and partner-to-HNRNPKP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi lumen acidification grouped by HNRNPKP5-low versus HNRNPKP5-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPKP5→partner) and Y-score (partner→HNRNPKP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Golgi lumen acidification →	+0.049	+0.245	<.001	<.001	3	21
UVM	Regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.047	+0.254	<.001	<.001	3	21
ESCA	Positive regulation of amide metabolic process →	+0.065	+0.478	<.001	<.001	3	21
ESCA	Macromolecule methylation →	+0.051	+0.411	.001	<.001	2	21
ESCA	Protein deacetylation →	+0.050	+0.481	<.001	<.001	2	21
KIRC	Base-excision repair, AP site formation →	+0.052	+0.278	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,993 associations by consensus.

Golgi lumen acidification by HNRNPKP5 expression — STAD

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