HNRNPKP5

Across TCGA pan-cancer cohorts, HNRNPKP5 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HNRNPKP5’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where HNRNPKP5 RNA is repressed in tumor relative to normal tissue. In most cancer types HNRNPKP5 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, LIHC, and UCEC are the cancer types where HNRNPKP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HNRNPKP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.315	<.001	6	view →
LIHC	Male	All	+0.062	.004	3	view →
UCEC	All	II,III,IV	−0.383	.040	2	view →
COAD	All	All	+0.125	.046	1	view →
LUSC	All	All	+0.107	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

HNRNPKP5–BRCA

Open the BRCA breakdown →