HNRNPH2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HNRNPH2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HNRNPH2-associated genes across cancer lineages are TEX51, CPLX4, and ACSM6. Each is linked with HNRNPH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPH2-to-partner and partner-to-HNRNPH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX51 grouped by HNRNPH2-low versus HNRNPH2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPH2→partner) and Y-score (partner→HNRNPH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaTEX51 →+0.026+5.643<.001.00231
LARGE_INTESTINECPLX4 →+0.044+4.392<.001.00431
LARGE_INTESTINEACSM6 →+0.031+4.584<.001<.00131
LARGE_INTESTINECFHR2 →+0.046+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TEX51 by HNRNPH2 expression — BLOOD_Lymphoma

Box plot of TEX51 in HNRNPH2-low vs HNRNPH2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration