HNRNPDL

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HNRNPDL mutation is significantly associated with the RNA expression of many other genes, with 1,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPDL-associated genes across cancer lineages are RN7SL248P, MIR6795, and C18orf12. Each is linked with HNRNPDL in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPDL-to-partner and partner-to-HNRNPDL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by HNRNPDL-low versus HNRNPDL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPDL→partner) and Y-score (partner→HNRNPDL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.060+3.219<.001.00432
UCECMIR6795 →+0.195+3.890<.001.00732
LUSCC18orf12 →+0.138+5.093<.001.00832
HNSCDYNLL1P5 →+0.153+5.578<.001.00432
HNSCOR10H4 →+0.052+5.015.008.00932
HNSCKRTAP2-1 →+0.121+6.936<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,041 associations by consensus.

RN7SL248P by HNRNPDL expression — UCEC

Box plot of RN7SL248P in HNRNPDL-low vs HNRNPDL-high samples in UCEC.

Explore this box plot interactively →

Exploration