HNRNPD

Across TCGA cell cohorts, HNRNPD mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HNRNPD-associated genes across cancer lineages are IQCF5, ACOD1, and ANKRD66. Each is linked with HNRNPD in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPD-to-partner and partner-to-HNRNPD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF5 grouped by HNRNPD-low versus HNRNPD-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPD→partner) and Y-score (partner→HNRNPD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	IQCF5 →	+0.056	+5.357	<.001	.003	3	1
STOMACH	ACOD1 →	+0.006	+5.285	<.001	.003	3	1
BLOOD_Leukemia	ANKRD66 →	+0.241	+4.922	<.001	.009	3	1
CNS	GK2 →	+0.013	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IQCF5 by HNRNPD expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →