HNRNPA2B1

Across TCGA pan-cancer cohorts, HNRNPA2B1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated HNRNPA2B1 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HNRNPA2B1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HNRNPA2B1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

HNSC, LUAD, and PDAC are the cancer types where HNRNPA2B1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	IV	0.134	1.000	.008	45	view →
LUAD	DFS	Quartile	All	0.929	0.394	.001	29	view →
PDAC	DFS	Quartile	All	0.944	0.677	.008	6	view →
CCRCC	DFS	Median	II,III,IV	0.745	0.481	.011	6	view →
UCEC	DFS	Median	II,III,IV	0.538	0.863	.044	4	view →
LSCC	DFS	Median	II,III,IV	0.868	0.696	.025	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

HNRNPA2B1–HNSC (OS)

Open the HNSC breakdown →