HNRNPA1P66

Across TCGA patient cohorts, HNRNPA1P66 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,845 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HNRNPA1P66-associated GO terms across cancer lineages are Positive regulation of telomere maintenance via telomere lengthening, RNA localization, and Protein localization to chromosome. Each is linked with HNRNPA1P66 in more than 21 cancer types. Because this analysis shows association rather than direction, both HNRNPA1P66-to-partner and partner-to-HNRNPA1P66 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomere maintenance via telomere lengthening grouped by HNRNPA1P66-low versus HNRNPA1P66-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1P66→partner) and Y-score (partner→HNRNPA1P66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Positive regulation of telomere maintenance via telomere lengthening →	+0.057	+0.359	<.001	<.001	3	22
ESCA	RNA localization →	+0.063	+0.101	.001	<.001	3	22
STAD	Protein localization to chromosome →	+0.040	+0.100	<.001	<.001	3	22
ESCA	Regulation of DNA biosynthetic process →	+0.051	+0.085	.005	<.001	2	22
ESCA	Telomere maintenance →	+0.052	+0.089	.005	<.001	3	21
ESCA	Establishment of RNA localization →	+0.044	+0.079	.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,845 associations by consensus.

Positive regulation of telomere maintenance via telomere lengthening by HNRNPA1P66 expression — LAML

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