HNRNPA1P66

Across TCGA pan-cancer cohorts, HNRNPA1P66 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated HNRNPA1P66 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher HNRNPA1P66 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HNRNPA1P66 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

KIRC, STAD, and ACC are the cancer types where HNRNPA1P66 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.716	0.835	<.001	120	view →
STAD	DFS	Median	IV	0.139	0.643	<.001	47	view →
ACC	OS	Quartile	All	0.282	0.844	.001	37	view →
BLCA	DFS	Quartile	III,IV	0.247	0.562	<.001	36	view →
READ	OS	Quartile	III,IV	0.813	0.296	.005	27	view →
PCPG	OS	Tertile	All	0.603	0.990	.001	18	view →
DLBC	DFS	Tertile	All	0.414	0.924	.008	18	view →
SKCM	OS	Median	All	0.413	0.285	.007	17	view →
LUAD	OS	Quartile	All	0.160	0.420	.002	15	view →
HNSC	OS	Tertile	All	0.274	0.419	.012	15	view →
CHOL	OS	Tertile	III,IV	0.208	0.948	.010	15	view →
ESCA	DFS	Median	III,IV	0.323	0.530	.020	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

HNRNPA1P66–KIRC (DFS)

Open the KIRC breakdown →