HNRNPA1P58

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, HNRNPA1P58 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated HNRNPA1P58 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher HNRNPA1P58 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated HNRNPA1P58 expression acts as an unfavorable survival marker, although some lineages such as HNSC and THCA show a favorable association.

HNSC, STAD, and THCA are the cancer types where HNRNPA1P58 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCDFSMedianIV0.7830.605.00250view →
STADDFSQuartileIII,IV0.2020.646.01421view →
THCADFSTertileAll0.9180.803.01918view →
OVDFSQuartileIII,IV0.2980.390.01418view →
UCSDFSMedianIV0.9090.416.00818view →
CHOLOSTertileAll1.0000.641.02412view →
LUADOSTertileAll0.5740.708.02912view →
SKCMOSQuartileAll0.9600.829.0109view →
PCPGOSTertileAll0.9161.000.0109view →
PRADDFSTertileAll0.8910.720.0188view →
ESCADFSTertileIV0.3040.704.0246view →
LUSCOSQuartileII,III,IV0.5270.324.0175view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration