HNRNPA1L2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HNRNPA1L2 mutation is significantly associated with the RNA expression of many other genes, with 380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA1L2-associated genes across cancer lineages are LINC00396, RPS15AP27, and RN7SL310P. Each is linked with HNRNPA1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA1L2-to-partner and partner-to-HNRNPA1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00396 grouped by HNRNPA1L2-low versus HNRNPA1L2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1L2→partner) and Y-score (partner→HNRNPA1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADLINC00396 →+0.095+3.572.001.00732
UCECRPS15AP27 →+0.121+2.900<.001.00232
SKCMRN7SL310P →+0.188+4.665<.001<.00131
SKCMRN7SL504P →+0.066+5.163<.001.00231
SKCMRN7SL643P →+0.068+4.671<.001.00431
SKCMRPL21P127 →+0.159+3.613.004.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 380 associations by consensus.

LINC00396 by HNRNPA1L2 expression — LUAD

Box plot of LINC00396 in HNRNPA1L2-low vs HNRNPA1L2-high samples in LUAD.

Explore this box plot interactively →

Exploration