HNRNPA1

Across TCGA patient cohorts, HNRNPA1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,384 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HNRNPA1-associated genes across cancer lineages are SPAG5, SHMT2, and RAD51AP1. Each is linked with HNRNPA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HNRNPA1-to-partner and partner-to-HNRNPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNRNPA1 versus SPAG5 in BRCA, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1→partner) and Y-score (partner→HNRNPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPAG5 →	+1.184	+0.474	<.001	<.001	3	6
LSCC	SHMT2 →	+0.547	+0.273	<.001	<.001	3	5
BRCA	RAD51AP1 →	+0.960	+0.394	<.001	<.001	3	5
LSCC	TIMELESS →	+0.776	+0.383	<.001	<.001	3	5
LSCC	PA2G4 →	+0.566	+0.430	<.001	<.001	3	5
BRCA	CTPS1 →	+0.625	+0.365	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,384 associations by consensus.

HNRNPA1 vs SPAG5 — BRCA

Explore this scatter interactively →