HNRNPA1

Across TCGA patient cohorts, HNRNPA1 mutation is significantly associated with the RNA expression of many other genes, with 1,144 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA1-associated genes across cancer lineages are RN7SKP15, MIR615, and RPL12P2. Each is linked with HNRNPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA1-to-partner and partner-to-HNRNPA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP15 grouped by HNRNPA1-low versus HNRNPA1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA1→partner) and Y-score (partner→HNRNPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP15 →	+0.056	+4.475	<.001	.005	3	2
SKCM	MIR615 →	+0.354	+3.543	.002	.002	3	2
BLCA	RPL12P2 →	+0.181	+3.347	.002	.008	3	2
BLCA	RPL35AP37 →	+0.072	+3.177	<.001	.008	3	2
LUAD	RNU6-452P →	+0.202	+4.523	<.001	.004	3	2
LUAD	RNY1P7 →	+0.304	+4.707	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,144 associations by consensus.

RN7SKP15 by HNRNPA1 expression — SKCM

Explore this box plot interactively →