HNRNPA0

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HNRNPA0 mutation is significantly associated with the RNA expression of many other genes, with 262 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNRNPA0-associated genes across cancer lineages are MIR615, RNU6-391P, and AQP7P2. Each is linked with HNRNPA0 in more than 1 cancer types. Because this analysis shows association rather than direction, both HNRNPA0-to-partner and partner-to-HNRNPA0 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR615 grouped by HNRNPA0-low versus HNRNPA0-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNRNPA0→partner) and Y-score (partner→HNRNPA0) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR615 →+0.964+4.693<.001.00732
LUADRNU6-391P →+0.202+7.930<.001.00832
UCECAQP7P2 →+0.246+3.232<.001<.00132
UCECRNA5SP405 →+0.569+4.359<.001<.00132
UCECRNU6-151P →+0.452+2.741.009.00432
UCECE2F6P1 →+0.041+4.245<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 262 associations by consensus.

MIR615 by HNRNPA0 expression — COAD

Box plot of MIR615 in HNRNPA0-low vs HNRNPA0-high samples in COAD.

Explore this box plot interactively →

Exploration