HNF4G

Across TCGA patient cohorts, HNF4G RNA expression is significantly associated with the protein abundance of many other proteins, with 11,830 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HNF4G-associated proteins across cancer lineages are HNF4G_S121, PLEKHA6_S777, and PLS1. Each is linked with HNF4G in more than 6 cancer types. Because this analysis shows association rather than direction, both HNF4G-to-partner and partner-to-HNF4G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNF4G versus HNF4G_S121 in UCEC, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HNF4G→partner) and Y-score (partner→HNF4G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HNF4G_S121 →	+1.083	+1.357	<.001	<.001	3	7
PDAC	PLEKHA6_S777 →	+1.229	+0.917	<.001	<.001	3	5
HNSC	PLS1 →	+0.650	+0.897	<.001	<.001	3	5
UCEC	VIL1 →	+1.380	+1.128	<.001	<.001	3	5
HNSC	RHPN2 →	+0.519	+1.170	.001	<.001	3	4
UCEC	GOLM1 →	+0.614	+1.123	.009	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,830 associations by consensus.

HNF4G vs HNF4G_S121 — UCEC

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