HNF4G

Across TCGA patient cohorts, HNF4G mutation is significantly associated with the RNA expression of many other genes, with 1,882 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HNF4G-associated genes across cancer lineages are RN7SL869P, RNU4-61P, and VPS13B-DT. Each is linked with HNF4G in more than 2 cancer types. Because this analysis shows association rather than direction, both HNF4G-to-partner and partner-to-HNF4G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL869P grouped by HNF4G-low versus HNF4G-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNF4G→partner) and Y-score (partner→HNF4G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL869P →	+0.095	+4.684	<.001	<.001	3	3
UCEC	RNU4-61P →	+0.276	+1.924	.001	.001	3	3
SKCM	VPS13B-DT →	+0.403	+1.857	.009	.004	3	3
LUAD	SNORD3G →	+0.663	+4.786	<.001	.003	3	2
LUSC	RNU6-136P →	+0.541	+3.142	<.001	.001	3	2
LUAD	GLULP5 →	+0.020	+4.590	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,882 associations by consensus.

RN7SL869P by HNF4G expression — LUSC

Explore this box plot interactively →