HNF1A

Across TCGA patient cohorts, HNF1A RNA expression is significantly associated with the RNA expression of many other genes, with 16,517 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible HNF1A-associated genes across cancer lineages are HNF1A-AS1, VIL1, and SGK2. Each is linked with HNF1A in more than 26 cancer types. Because this analysis shows association rather than direction, both HNF1A-to-partner and partner-to-HNF1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HNF1A versus HNF1A-AS1 in ESCA, with a Pearson correlation of 0.97.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HNF1A→partner) and Y-score (partner→HNF1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	HNF1A-AS1 →	+4.384	+3.626	<.001	<.001	3	27
ESCA	VIL1 →	+5.466	+3.564	<.001	<.001	3	23
ESCA	SGK2 →	+3.057	+3.133	<.001	<.001	3	22
ESCA	SLC39A5 →	+3.212	+3.351	<.001	<.001	3	21
KIRP	SLC23A1 →	+1.178	+1.086	<.001	<.001	3	21
ESCA	BCAR3-AS1 →	+2.335	+3.317	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,517 associations by consensus.

HNF1A vs HNF1A-AS1 — ESCA

Explore this scatter interactively →