Across TCGA patient cohorts, HMX2 mutation is significantly associated with the RNA expression of many other genes, with 173 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMX2-associated genes across cancer lineages are VTRNA3-1P, CYCSP49, and LINC02307. Each is linked with HMX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMX2-to-partner and partner-to-HMX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMX2→partner) and Y-score (partner→HMX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	VTRNA3-1P →	+0.212	+4.070	<.001	.009	3	2
COAD	CYCSP49 →	+0.130	+4.821	<.001	.003	3	2
COAD	LINC02307 →	+0.239	+4.375	<.001	.001	3	2
STAD	RNU6-441P →	+0.734	+5.366	<.001	.005	3	2
LUAD	OR11H2 →	+0.080	+5.444	<.001	.002	3	2
UCEC	RNU6-698P →	+0.137	+4.245	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 173 associations by consensus.

Exploration

HMX2 survival (RNA) · tumor vs normal (RNA) · all HMX2 data types