HMGXB4

Across TCGA cell cohorts, HMGXB4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,891 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HMGXB4-associated genes across cancer lineages are TNRC6B, PITPNB, and EIF4ENIF1. Each is linked with HMGXB4 in more than 18 cancer types. Because this analysis shows association rather than direction, both HMGXB4-to-partner and partner-to-HMGXB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGXB4 versus TNRC6B in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGXB4→partner) and Y-score (partner→HMGXB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TNRC6B →	+1.352	+1.107	<.001	<.001	3	19
BLOOD_Myeloma	PITPNB →	+1.261	+0.811	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	EIF4ENIF1 →	+0.909	+0.847	<.001	<.001	3	19
LARGE_INTESTINE	MIEF1 →	+0.941	+0.843	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	PRR14L →	+1.184	+1.336	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	DDX17 →	+1.592	+0.950	.002	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,891 associations by consensus.

HMGXB4 vs TNRC6B — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →