HMGXB3

Across TCGA cell cohorts, HMGXB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,666 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HMGXB3-associated GO terms across cancer lineages are Microtubule polymerization, Microtubule nucleation, and Nuclear export. Each is linked with HMGXB3 in more than 13 cancer types. Because this analysis shows association rather than direction, both HMGXB3-to-partner and partner-to-HMGXB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by HMGXB3-low versus HMGXB3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGXB3→partner) and Y-score (partner→HMGXB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule polymerization →	+0.106	+0.927	<.001	<.001	3	14
LARGE_INTESTINE	Microtubule nucleation →	+0.117	+0.907	<.001	<.001	3	14
BLOOD_Lymphoma	Nuclear export →	+0.089	+1.061	<.001	<.001	3	13
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.139	+0.648	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.084	+1.214	<.001	<.001	3	12
BLOOD_Lymphoma	Protein deubiquitination →	+0.046	+0.918	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,666 associations by consensus.

Microtubule polymerization by HMGXB3 expression — LARGE_INTESTINE

Explore this box plot interactively →