HMGN4

Across TCGA patient cohorts, HMGN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,612 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGN4-associated proteins across cancer lineages are HPF1, CMTR1, and DAXX. Each is linked with HMGN4 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGN4-to-partner and partner-to-HMGN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGN4 versus HPF1 in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN4→partner) and Y-score (partner→HMGN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HPF1 →	+0.276	+0.334	.002	.009	2	7
LSCC	CMTR1 →	+0.317	+0.405	<.001	<.001	3	5
GBM	DAXX →	+0.275	+0.296	<.001	<.001	3	5
LSCC	GNL1 →	+0.269	+0.477	<.001	<.001	3	5
LSCC	WRNIP1 →	+0.356	+0.476	<.001	<.001	3	5
OV	RIOK1 →	+0.481	+0.479	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,612 associations by consensus.

HMGN4 vs HPF1 — LSCC

Explore this scatter interactively →