HMGN2P27

Across TCGA pan-cancer cohorts, HMGN2P27 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated HMGN2P27 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher HMGN2P27 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN2P27 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

LIHC, LUSC, and SKCM are the cancer types where HMGN2P27 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.337	0.488	<.001	67	view →
LUSC	DFS	Median	III,IV	0.310	0.997	<.001	59	view →
SKCM	OS	Tertile	All	0.937	0.867	<.001	42	view →
UVM	DFS	Tertile	III,IV	0.374	0.749	.009	42	view →
ACC	OS	Quartile	All	0.256	0.916	<.001	37	view →
LUAD	DFS	Tertile	III,IV	0.327	0.565	.011	35	view →
SARC	OS	Median	All	0.349	0.621	<.001	27	view →
CESC	DFS	Median	All	0.871	0.766	.007	14	view →
READ	OS	Median	III,IV	0.563	0.955	.008	13	view →
ESCA	OS	Tertile	IV	0.219	0.856	.024	12	view →
LGG	DFS	Tertile	All	0.673	0.819	.006	11	view →
THYM	DFS	Median	All	0.962	0.658	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

HMGN2P27–LIHC (DFS)

Open the LIHC breakdown →