Across TCGA pan-cancer cohorts, HMGN2P24 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of HMGN2P24’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HMGN2P24 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN2P24 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

COAD, LUSC, and KIRP are the cancer types where HMGN2P24 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN2P24 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.212	.015	2	view →
LUSC	Male	II,III,IV	+0.163	.035	1	view →
KIRP	Male	All	−0.079	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: HMGN2P24 RNA expression & survival · all HMGN2P24 data types