HMGN2P10

Across TCGA patient cohorts, HMGN2P10 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,259 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGN2P10-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle phase transition, Spindle organization, and Regulation of DNA damage checkpoint. Each is linked with HMGN2P10 in more than 21 cancer types. Because this analysis shows association rather than direction, both HMGN2P10-to-partner and partner-to-HMGN2P10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic cell cycle phase transition grouped by HMGN2P10-low versus HMGN2P10-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN2P10→partner) and Y-score (partner→HMGN2P10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of mitotic cell cycle phase transition →	+0.056	+0.245	.001	<.001	3	22
STAD	Spindle organization →	+0.056	+0.254	<.001	<.001	3	21
STAD	Regulation of DNA damage checkpoint →	+0.061	+0.267	<.001	<.001	3	21
ESCA	Negative regulation of mitotic cell cycle →	+0.052	+0.293	.002	<.001	3	21
ESCA	DNA replication →	+0.059	+0.279	.002	<.001	3	20
ESCA	Regulation of DNA replication →	+0.059	+0.251	.002	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,259 associations by consensus.

Negative regulation of mitotic cell cycle phase transition by HMGN2P10 expression — ESCA

Explore this box plot interactively →