HMGN2P10

Across TCGA pan-cancer cohorts, HMGN2P10 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of HMGN2P10’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where HMGN2P10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN2P10 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.

BRCA and PAAD are the cancer types where HMGN2P10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN2P10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	+0.079	.011	4	view →
PAAD	Female	All	−0.454	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

HMGN2P10–BRCA

Open the BRCA breakdown →