Across TCGA patient cohorts, HMGN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,029 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGN2-associated proteins across cancer lineages are MCM7, STMN1, and MCM3. Each is linked with HMGN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGN2-to-partner and partner-to-HMGN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN2→partner) and Y-score (partner→HMGN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM7 →	+0.800	+0.666	<.001	<.001	3	8
OV	STMN1 →	+0.674	+0.675	<.001	<.001	3	8
LSCC	MCM3 →	+0.826	+0.647	<.001	<.001	3	7
LSCC	UHRF1 →	+0.696	+0.581	<.001	<.001	3	7
GBM	USP48 →	+0.424	+0.709	<.001	<.001	3	7
GBM	RCC2 →	+0.396	+0.603	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,029 associations by consensus.

Exploration

HMGN2 survival (RNA) · tumor vs normal (RNA) · all HMGN2 data types