Across TCGA patient cohorts, HMGN2 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMGN2-associated genes across cancer lineages are SNORD3H, RN7SL717P, and MIR3118-3. Each is linked with HMGN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HMGN2-to-partner and partner-to-HMGN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN2→partner) and Y-score (partner→HMGN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNORD3H →	+0.377	+5.288	<.001	.006	3	2
BLCA	RN7SL717P →	+0.186	+5.497	<.001	.004	3	2
BRCA	MIR3118-3 →	+0.371	+7.471	<.001	.008	3	1
BLCA	OR11H2 →	+0.066	+5.588	<.001	.004	3	1
UCEC	RNA5SP357 →	+0.889	+3.881	<.001	.004	3	1
UCEC	RNA5SP411 →	+1.338	+3.393	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

HMGN2 survival (RNA) · tumor vs normal (RNA) · all HMGN2 data types