HMGN1P33

Across TCGA pan-cancer cohorts, HMGN1P33 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated HMGN1P33 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher HMGN1P33 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN1P33 expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

ACC, MESO, and KIRP are the cancer types where HMGN1P33 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.061	0.675	<.001	66	view →
MESO	DFS	Tertile	All	0.376	0.200	.011	44	view →
KIRP	DFS	Tertile	IV	0.031	0.393	.034	27	view →
HNSC	DFS	Tertile	II,III,IV	0.452	0.608	.017	24	view →
THCA	DFS	Tertile	III,IV	0.737	0.931	.002	21	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	18	view →
LAML	DFS	Tertile	All	0.233	0.594	.036	18	view →
READ	DFS	Tertile	IV	0.082	0.619	.001	18	view →
LIHC	DFS	Tertile	III,IV	0.138	0.344	.048	9	view →
KIRC	OS	Tertile	All	0.544	0.650	.046	3	view →
LUAD	OS	Tertile	All	0.713	0.819	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

HMGN1P33–ACC (DFS)

Open the ACC breakdown →