HMGN1P32

Across TCGA pan-cancer cohorts, HMGN1P32 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated HMGN1P32 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher HMGN1P32 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated HMGN1P32 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

LIHC, STAD, and KIRC are the cancer types where HMGN1P32 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	III,IV	0.140	0.661	<.001	81	view →
STAD	OS	Tertile	II,III,IV	0.263	0.607	<.001	54	view →
KIRC	OS	Tertile	II,III,IV	0.354	0.555	.005	51	view →
ESCA	DFS	Tertile	III,IV	0.589	0.258	.017	36	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	36	view →
GBM	OS	Tertile	All	0.211	0.432	<.001	27	view →
BLCA	OS	Tertile	IV	0.253	0.606	.026	21	view →
LGG	OS	Tertile	All	0.467	0.815	.003	21	view →
SKCM	DFS	Tertile	II,III,IV	0.334	0.716	.003	18	view →
PCPG	DFS	Tertile	All	0.091	0.768	.007	18	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
HNSC	DFS	Tertile	All	0.374	0.335	.025	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

HMGN1P32–LIHC (OS)

Open the LIHC breakdown →