HMGN1P20

Across TCGA patient cohorts, HMGN1P20 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,261 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGN1P20-associated GO terms across cancer lineages are DNA integrity checkpoint signaling, Regulation of microtubule-based process, and rRNA metabolic process. Each is linked with HMGN1P20 in more than 9 cancer types. Because this analysis shows association rather than direction, both HMGN1P20-to-partner and partner-to-HMGN1P20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA integrity checkpoint signaling grouped by HMGN1P20-low versus HMGN1P20-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGN1P20→partner) and Y-score (partner→HMGN1P20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	DNA integrity checkpoint signaling →	+0.037	+0.238	<.001	<.001	3	10
STAD	Regulation of microtubule-based process →	+0.030	+0.150	<.001	<.001	3	10
STAD	rRNA metabolic process →	+0.058	+0.189	<.001	<.001	3	9
STAD	RNA localization →	+0.038	+0.102	<.001	.002	3	9
STAD	RNA modification →	+0.048	+0.180	<.001	<.001	2	10
ESCA	Mitochondrial RNA processing →	+0.050	+0.175	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,261 associations by consensus.

DNA integrity checkpoint signaling by HMGN1P20 expression — LAML

Explore this box plot interactively →