HMGN1P20

Across TCGA pan-cancer cohorts, HMGN1P20 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HMGN1P20’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where HMGN1P20 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HMGN1P20 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

LUAD, THCA, and KIRC are the cancer types where HMGN1P20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HMGN1P20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	All	+0.108	.005	3	view →
THCA	All	All	−0.056	.001	3	view →
KIRC	Male	IV	−0.047	.035	3	view →
BRCA	All	II,III,IV	+0.053	.045	2	view →
KICH	All	II,III,IV	+0.098	.041	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

HMGN1P20–LUAD

Open the LUAD breakdown →