HMGN1P14

Across TCGA pan-cancer cohorts, HMGN1P14 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated HMGN1P14 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher HMGN1P14 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HMGN1P14 expression acts as an unfavorable survival marker, although some lineages such as ESCA and PAAD show a favorable association.

UCS, ACC, and KIRC are the cancer types where HMGN1P14 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.168	0.505	.002	72	view →
ACC	OS	Tertile	All	0.516	0.937	<.001	63	view →
KIRC	OS	Median	All	0.518	0.702	<.001	48	view →
READ	DFS	Tertile	IV	0.082	0.619	.001	45	view →
ESCA	OS	Tertile	III,IV	0.827	0.452	.001	36	view →
LGG	OS	Tertile	All	0.166	0.541	<.001	27	view →
STAD	DFS	Quartile	IV	0.087	0.400	.012	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	18	view →
PAAD	OS	Tertile	All	0.905	0.427	.012	18	view →
LUAD	DFS	Tertile	IV	0.223	0.710	.043	18	view →
SARC	OS	Tertile	All	0.702	0.850	.003	18	view →
HNSC	DFS	Tertile	II,III,IV	0.266	0.569	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

HMGN1P14–UCS (DFS)

Open the UCS breakdown →