HMGN1P10

Across TCGA pan-cancer cohorts, HMGN1P10 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated HMGN1P10 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HMGN1P10 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated HMGN1P10 expression acts as an unfavorable survival marker, although some lineages such as COAD and OV show a favorable association.

COAD, KIRC, and OV are the cancer types where HMGN1P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	II,III,IV	0.930	0.740	.010	42	view →
KIRC	OS	Tertile	All	0.533	0.650	.011	36	view →
OV	OS	Quartile	II,III,IV	0.433	0.330	.006	34	view →
LIHC	DFS	Tertile	II,III,IV	0.086	0.429	.009	24	view →
PCPG	OS	Tertile	All	0.571	0.963	<.001	18	view →
READ	DFS	Tertile	II,III,IV	0.425	0.729	.047	18	view →
SKCM	OS	Tertile	III,IV	0.273	0.729	.001	15	view →
STAD	OS	Quartile	IV	0.618	0.209	.021	12	view →
LUSC	OS	Tertile	II,III,IV	0.854	0.723	.028	12	view →
LUAD	DFS	Tertile	IV	0.671	0.893	.019	12	view →
PAAD	DFS	Tertile	All	0.332	0.478	.043	9	view →
ESCA	OS	Median	II,III,IV	0.627	0.762	.036	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

HMGN1P10–COAD (DFS)

Open the COAD breakdown →