HMGCL

Across TCGA patient cohorts, HMGCL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,787 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HMGCL-associated proteins across cancer lineages are GALE, NMNAT1, and ARHGEF16. Each is linked with HMGCL in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGCL-to-partner and partner-to-HMGCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGCL versus GALE in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGCL→partner) and Y-score (partner→HMGCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GALE →	+0.590	+0.453	<.001	<.001	3	7
OV	NMNAT1 →	+0.432	+0.521	<.001	<.001	3	7
CCRCC	ARHGEF16 →	+0.396	+0.431	<.001	<.001	3	6
OV	RPS6KA1 →	+0.401	+0.391	<.001	.002	3	5
BRCA	DDAH1 →	+0.604	+0.735	<.001	<.001	3	5
CCRCC	DNAJB11 →	-0.475	-0.458	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,787 associations by consensus.

HMGCL vs GALE — LSCC

Explore this scatter interactively →