Across TCGA patient cohorts, HMGB3P30 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,682 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB3P30-associated GO terms across cancer lineages are Sister chromatid segregation, Signal transduction in response to DNA damage, and Regulation of cell cycle G2/M phase transition. Each is linked with HMGB3P30 in more than 11 cancer types. Because this analysis shows association rather than direction, both HMGB3P30-to-partner and partner-to-HMGB3P30 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P30→partner) and Y-score (partner→HMGB3P30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Sister chromatid segregation →	+0.063	+0.052	<.001	<.001	3	12
STAD	Signal transduction in response to DNA damage →	+0.049	+0.044	<.001	<.001	3	12
STAD	Regulation of cell cycle G2/M phase transition →	+0.048	+0.042	<.001	<.001	3	11
STAD	Positive regulation of protein modification by small protein conjugation or removal →	+0.052	+0.066	<.001	<.001	3	11
STAD	DNA replication →	+0.055	+0.052	<.001	<.001	3	11
STAD	Recombinational repair →	+0.049	+0.047	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,682 associations by consensus.

Exploration

HMGB3P30 survival (RNA) · tumor vs normal (RNA) · all HMGB3P30 data types