Across TCGA patient cohorts, HMGB3P22 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,223 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HMGB3P22-associated proteins across cancer lineages are AKAP13_S2709, ERI3, and FAM120C. Each is linked with HMGB3P22 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB3P22-to-partner and partner-to-HMGB3P22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB3P22→partner) and Y-score (partner→HMGB3P22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AKAP13_S2709 →	-0.538	-0.401	<.001	<.001	3	4
OV	ERI3 →	+0.282	+0.740	.005	.004	3	4
BRCA	FAM120C →	+0.413	+0.528	<.001	<.001	3	4
OV	WIPF1 →	-0.359	-0.742	.006	.002	3	4
GBM	ZMYM3 →	+0.268	+0.477	.001	.002	3	3
GBM	RCSD1_S351 →	-0.456	-0.496	.003	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,223 associations by consensus.

Exploration

HMGB3P22 survival (RNA) · tumor vs normal (RNA) · all HMGB3P22 data types