HMGB1P51

Across TCGA patient cohorts, HMGB1P51 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,349 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HMGB1P51-associated proteins across cancer lineages are NCOR2_S1479, EIF4B_S207, and GORASP1_S220. Each is linked with HMGB1P51 in more than 2 cancer types. Because this analysis shows association rather than direction, both HMGB1P51-to-partner and partner-to-HMGB1P51 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P51 versus NCOR2_S1479 in CCRCC, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P51→partner) and Y-score (partner→HMGB1P51) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NCOR2_S1479 →	-0.562	-0.470	<.001	<.001	3	3
PDAC	EIF4B_S207 →	-0.379	-0.432	.002	.003	3	3
UCEC	GORASP1_S220 →	-0.806	-0.899	.003	.001	3	3
LSCC	HNRNPM_S528 →	-0.714	-0.287	<.001	.008	3	3
LSCC	WDR20_S353 →	-0.483	-0.423	<.001	.001	3	3
LSCC	TERF2IP_S203 →	-0.348	-0.279	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,349 associations by consensus.

HMGB1P51 vs NCOR2_S1479 — CCRCC

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