Across TCGA patient cohorts, HMGB1P45 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,405 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P45-associated GO terms across cancer lineages are Positive regulation of cell cycle process, Positive regulation of mitotic cell cycle, and Mitotic nuclear division. Each is linked with HMGB1P45 in more than 16 cancer types. Because this analysis shows association rather than direction, both HMGB1P45-to-partner and partner-to-HMGB1P45 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P45→partner) and Y-score (partner→HMGB1P45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of cell cycle process →	+0.058	+0.216	<.001	.001	3	16
ESCA	Positive regulation of mitotic cell cycle →	+0.056	+0.204	.001	<.001	2	17
ESCA	Mitotic nuclear division →	+0.065	+0.232	<.001	<.001	3	16
ESCA	Mitotic sister chromatid segregation →	+0.072	+0.222	<.001	<.001	3	16
ESCA	Metaphase chromosome alignment →	+0.072	+0.216	<.001	<.001	3	16
ESCA	Mitotic metaphase chromosome alignment →	+0.085	+0.288	.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,405 associations by consensus.

Exploration

HMGB1P45 survival (RNA) · tumor vs normal (RNA) · all HMGB1P45 data types