HMGB1P41

Across TCGA patient cohorts, HMGB1P41 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,006 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HMGB1P41-associated proteins across cancer lineages are ZNF704_S77, BTK, and DDAH1. Each is linked with HMGB1P41 in more than 6 cancer types. Because this analysis shows association rather than direction, both HMGB1P41-to-partner and partner-to-HMGB1P41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P41 versus ZNF704_S77 in LUAD, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P41→partner) and Y-score (partner→HMGB1P41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ZNF704_S77 →	+1.044	+1.195	<.001	<.001	3	7
LSCC	BTK →	-0.455	-0.986	.001	.001	3	6
LUAD	DDAH1 →	+0.664	+0.971	<.001	<.001	3	6
GBM	PIK3CG_S974 →	-0.765	-1.162	<.001	<.001	3	6
PDAC	UNC13D →	-0.460	-0.680	<.001	<.001	3	6
GBM	MYO1F →	-0.582	-0.824	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,006 associations by consensus.

HMGB1P41 vs ZNF704_S77 — LUAD

Explore this scatter interactively →