HMGB1P36

Across TCGA patient cohorts, HMGB1P36 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,634 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P36-associated GO terms across cancer lineages are Nucleoside phosphate biosynthetic process, Negative regulation of cellular catabolic process, and Establishment of protein localization to membrane. Each is linked with HMGB1P36 in more than 12 cancer types. Because this analysis shows association rather than direction, both HMGB1P36-to-partner and partner-to-HMGB1P36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside phosphate biosynthetic process grouped by HMGB1P36-low versus HMGB1P36-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P36→partner) and Y-score (partner→HMGB1P36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nucleoside phosphate biosynthetic process →	+0.069	+0.134	<.001	<.001	3	13
STAD	Negative regulation of cellular catabolic process →	+0.065	+0.145	<.001	<.001	3	12
STAD	Establishment of protein localization to membrane →	+0.074	+0.130	<.001	<.001	3	11
STAD	Organelle disassembly →	+0.075	+0.132	<.001	<.001	3	11
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.074	+0.135	<.001	<.001	3	11
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.074	+0.135	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,634 associations by consensus.

Nucleoside phosphate biosynthetic process by HMGB1P36 expression — STAD

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