HMGB1P30

Across TCGA patient cohorts, HMGB1P30 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,887 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P30-associated GO terms across cancer lineages are Protein localization to microtubule organizing center, Telomere organization, and Response to ionizing radiation. Each is linked with HMGB1P30 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGB1P30-to-partner and partner-to-HMGB1P30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to microtubule organizing center grouped by HMGB1P30-low versus HMGB1P30-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P30→partner) and Y-score (partner→HMGB1P30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to microtubule organizing center →	+0.055	+0.058	<.001	<.001	3	8
STAD	Telomere organization →	+0.061	+0.062	<.001	<.001	3	8
STAD	Response to ionizing radiation →	+0.062	+0.056	<.001	<.001	3	8
STAD	RNA methylation →	+0.057	+0.057	<.001	<.001	3	7
STAD	Regulation of DNA recombination →	+0.055	+0.067	<.001	<.001	3	7
STAD	Peptidyl-lysine acetylation →	+0.050	+0.056	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,887 associations by consensus.

Protein localization to microtubule organizing center by HMGB1P30 expression — STAD

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