HMGB1P28

Across TCGA patient cohorts, HMGB1P28 RNA expression is significantly associated with the RNA expression of many other genes, with 4,345 significant associations in total. PCPG shows the largest number of these associations.

The most reproducible HMGB1P28-associated genes across cancer lineages are RPL23P5, RPS7P10, and HNRNPA1P12. Each is linked with HMGB1P28 in more than 16 cancer types. Because this analysis shows association rather than direction, both HMGB1P28-to-partner and partner-to-HMGB1P28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P28 versus RPL23P5 in LAML, with a Pearson correlation of 0.36.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P28→partner) and Y-score (partner→HMGB1P28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	RPL23P5 →	+0.584	+0.199	<.001	<.001	3	17
READ	RPS7P10 →	+0.726	+0.094	<.001	<.001	3	15
LAML	HNRNPA1P12 →	+0.556	+0.276	<.001	<.001	3	15
LAML	RPL21P4 →	+0.557	+0.219	<.001	<.001	3	15
LUAD	EEF1A1P4 →	+0.578	+0.036	<.001	<.001	3	14
LAML	RPL7P32 →	+0.535	+0.191	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,345 associations by consensus.

HMGB1P28 vs RPL23P5 — LAML

Explore this scatter interactively →