HMGB1P23

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HMGB1P23 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,728 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMGB1P23-associated proteins across cancer lineages are KIF13B, MLPH, and RBPMS. Each is linked with HMGB1P23 in more than 3 cancer types. Because this analysis shows association rather than direction, both HMGB1P23-to-partner and partner-to-HMGB1P23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P23 versus KIF13B in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P23→partner) and Y-score (partner→HMGB1P23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCKIF13B →+0.356+0.790<.001<.00134
BRCAMLPH →+0.651+0.084.001.00433
PDACRBPMS →+0.361+0.469.001.00233
LSCCTEX2_S732 →-0.401-0.465.004.00233
LSCCSLC9A3R2 →+0.347+0.521<.001.00133
OVKIF13B_S1381 →+0.733+0.101.002.00824
Each partner links to its Q-omics profile. Showing the 6 strongest of 8,728 associations by consensus.

HMGB1P23 vs KIF13B — HNSC

Per-sample scatter of HMGB1P23 vs KIF13B in HNSC (Pearson r = 0.38).

Explore this scatter interactively →

Exploration