HMGB1P19

Across TCGA patient cohorts, HMGB1P19 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,299 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HMGB1P19-associated proteins across cancer lineages are SNRPD2, CPSF3, and H1-0. Each is linked with HMGB1P19 in more than 4 cancer types. Because this analysis shows association rather than direction, both HMGB1P19-to-partner and partner-to-HMGB1P19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P19 versus SNRPD2 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P19→partner) and Y-score (partner→HMGB1P19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD2 →	+0.305	+0.478	.001	<.001	3	5
LSCC	CPSF3 →	+0.212	+0.487	.002	.001	3	5
GBM	H1-0 →	-0.634	-0.402	.001	<.001	3	5
GBM	SMC2 →	+0.706	+0.421	<.001	<.001	3	5
LSCC	SUPT16H →	+0.437	+0.651	<.001	<.001	3	5
LSCC	THOC1 →	+0.333	+0.580	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,299 associations by consensus.

HMGB1P19 vs SNRPD2 — GBM

Explore this scatter interactively →