HMGB1P14

Across TCGA patient cohorts, HMGB1P14 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,345 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HMGB1P14-associated proteins across cancer lineages are PPP4R3A, SUPT16H, and IRF2BPL. Each is linked with HMGB1P14 in more than 5 cancer types. Because this analysis shows association rather than direction, both HMGB1P14-to-partner and partner-to-HMGB1P14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMGB1P14 versus PPP4R3A in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P14→partner) and Y-score (partner→HMGB1P14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPP4R3A →	+0.269	+0.402	.001	.003	3	6
GBM	SUPT16H →	+0.315	+0.469	<.001	<.001	3	4
LUAD	IRF2BPL →	+0.364	+0.549	<.001	<.001	3	4
BRCA	RPL3 →	-0.319	-0.427	.002	<.001	3	4
LUAD	RPL4 →	-0.328	-0.453	<.001	<.001	3	4
LUAD	RPS6_S240 →	-0.575	-0.357	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,345 associations by consensus.

HMGB1P14 vs PPP4R3A — LSCC

Explore this scatter interactively →