Across TCGA patient cohorts, HMGB1P13 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,286 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HMGB1P13-associated GO terms across cancer lineages are Microtubule organizing center organization, Methylation, and Ribosomal small subunit biogenesis. Each is linked with HMGB1P13 in more than 9 cancer types. Because this analysis shows association rather than direction, both HMGB1P13-to-partner and partner-to-HMGB1P13 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P13→partner) and Y-score (partner→HMGB1P13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microtubule organizing center organization →	+0.042	+0.089	.001	.003	3	10
STAD	Methylation →	+0.035	+0.065	<.001	<.001	3	10
STAD	Ribosomal small subunit biogenesis →	+0.050	+0.053	<.001	<.001	3	10
STAD	DNA-templated transcription initiation →	+0.042	+0.061	<.001	<.001	3	10
ESCA	Transcription initiation at RNA polymerase II promoter →	+0.047	+0.113	.001	.001	3	10
STAD	Transcription by RNA polymerase III →	+0.040	+0.050	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,286 associations by consensus.

Exploration

HMGB1P13 survival (RNA) · tumor vs normal (RNA) · all HMGB1P13 data types