Across TCGA patient cohorts, HMGB1P12 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,476 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HMGB1P12-associated GO terms across cancer lineages are Regulation of spindle organization, DNA replication, and Cell fate specification. Each is linked with HMGB1P12 in more than 7 cancer types. Because this analysis shows association rather than direction, both HMGB1P12-to-partner and partner-to-HMGB1P12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMGB1P12→partner) and Y-score (partner→HMGB1P12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of spindle organization →	+0.061	+0.116	<.001	<.001	3	8
STAD	DNA replication →	+0.068	+0.133	<.001	<.001	2	8
LAML	Cell fate specification →	+0.036	+0.094	<.001	<.001	3	7
STAD	Blastocyst development →	+0.056	+0.116	<.001	<.001	3	7
STAD	Negative regulation of DNA repair →	+0.056	+0.121	<.001	<.001	2	8
ESCA	Positive regulation of protein polyubiquitination →	+0.061	+0.128	<.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,476 associations by consensus.

Exploration

HMGB1P12 survival (RNA) · tumor vs normal (RNA) · all HMGB1P12 data types