HMG20B

Across TCGA patient cohorts, HMG20B RNA expression is significantly associated with the RNA expression of many other genes, with 20,100 significant associations in total. ACC shows the largest number of these associations.

The most reproducible HMG20B-associated genes across cancer lineages are MAP2K2, PRR22, and YJU2. Each is linked with HMG20B in more than 32 cancer types. Because this analysis shows association rather than direction, both HMG20B-to-partner and partner-to-HMG20B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMG20B versus MAP2K2 in DLBC, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMG20B→partner) and Y-score (partner→HMG20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	MAP2K2 →	+0.964	+0.577	<.001	<.001	3	33
ACC	PRR22 →	+1.240	+1.028	<.001	<.001	3	33
ACC	YJU2 →	+0.912	+1.031	<.001	<.001	3	33
ACC	DAPK3 →	+1.031	+1.018	<.001	<.001	3	32
ACC	SGTA →	+0.861	+0.967	<.001	<.001	3	32
ACC	LSM7 →	+1.238	+1.156	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,100 associations by consensus.

HMG20B vs MAP2K2 — DLBC

Explore this scatter interactively →