HMG20B

Across TCGA patient cohorts, HMG20B protein abundance is significantly associated with the RNA expression of many other genes, with 8,391 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMG20B-associated genes across cancer lineages are RRM1, BARD1, and CCDC34. Each is linked with HMG20B in more than 4 cancer types. Because this analysis shows association rather than direction, both HMG20B-to-partner and partner-to-HMG20B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMG20B versus RRM1 in UCEC, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMG20B→partner) and Y-score (partner→HMG20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM1 →	+0.732	+0.229	.001	.001	3	5
LSCC	BARD1 →	+0.615	+0.270	<.001	<.001	3	5
COAD	CCDC34 →	+0.952	+0.207	.002	.005	2	5
BRCA	CDT1 →	+1.094	+0.211	<.001	.003	3	4
UCEC	CTR9 →	+0.515	+0.254	.002	<.001	3	4
LSCC	POLD3 →	+0.559	+0.197	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,391 associations by consensus.

HMG20B vs RRM1 — UCEC

Explore this scatter interactively →