HMG20B

Across TCGA cell cohorts, HMG20B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,866 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible HMG20B-associated GO terms across cancer lineages are Positive regulation of anaphase-promoting complex-dependent catabolic process, Pigment metabolic process involved in pigmentation, and Regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with HMG20B in more than 18 cancer types. Because this analysis shows association rather than direction, both HMG20B-to-partner and partner-to-HMG20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anaphase-promoting complex-dependent catabolic process grouped by HMG20B-low versus HMG20B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HMG20B→partner) and Y-score (partner→HMG20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.157	+1.179	<.001	<.001	3	19
LUNG_NSCLC_LUAD	Pigment metabolic process involved in pigmentation →	+0.296	+0.747	<.001	<.001	3	15
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.188	+1.000	.003	.001	3	15
LUNG_NSCLC_LUSC	Phosphatidylinositol biosynthetic process →	+0.061	+1.264	.002	<.001	3	13
BONE	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.171	+1.383	<.001	<.001	3	13
URINARY_TRACT	Protein depolymerization →	+0.128	+0.843	.004	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

Positive regulation of anaphase-promoting complex-dependent catabolic process by HMG20B expression — BONE

Explore this box plot interactively →