HMG20A

Across TCGA patient cohorts, HMG20A protein abundance is significantly associated with the RNA expression of many other genes, with 14,418 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HMG20A-associated genes across cancer lineages are NUP88, METTL16, and RPAIN. Each is linked with HMG20A in more than 4 cancer types. Because this analysis shows association rather than direction, both HMG20A-to-partner and partner-to-HMG20A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HMG20A versus NUP88 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HMG20A→partner) and Y-score (partner→HMG20A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUP88 →	+0.666	+0.193	<.001	.001	3	5
LSCC	METTL16 →	+0.442	+0.187	<.001	<.001	3	5
BRCA	RPAIN →	+0.567	+0.178	<.001	.008	3	5
LSCC	TADA1 →	+0.650	+0.234	<.001	<.001	3	5
GBM	SPI1 →	-0.888	-0.312	<.001	.001	3	5
OV	IL16 →	-0.670	-0.262	.003	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,418 associations by consensus.

HMG20A vs NUP88 — UCEC

Explore this scatter interactively →